Panama City PANAMA CITY
Boquete BOQUETE
Isla Palenque ISLA PALENQUE
Bocas del Toro BOCAS DEL TORO

Panama is a country where tropical landscapes, vibrant culture, and extraordinary biodiversity come together between two oceans. Explore the cosmopolitan energy of Panama City, discover the historic streets of Casco Viejo, experience the engineering marvel of the Panama Canal, or venture into lush rainforests, remote islands, and coastal landscapes to encounter the country’s remarkable wildlife. Whether you’re seeking luxury, adventure, gastronomy, nature, or culture, Panama offers unforgettable experiences in every corner. Our tailor-made journeys combine carefully selected accommodations with authentic local experiences, allowing you to discover the country at your own pace.

Panama City & The Pacific Coast

This immersive Panamanian itinerary seamlessly pairs urban history and engineering marvels with pristine, untouched tropical nature. Transitioning from the vibrant streets and rainforests surrounding Panama City to a secluded private island in the Pacific, it offers an ideal balance of guided discovery, rich biodiversity, and exclusive beachside luxury.

Duration: 7 Days / 6 Nights 

Highlights:

  • Historic Panama City & Canal: Explore the cobblestone streets of UNESCO-listed Casco Viejo, sample fresh ceviche at the local fish market, and enjoy VIP access to the Miraflores Locks on the Panama Canal.
  • Rainforest & Gatún Lake Adventure: Hike through the biodiverse Soberanía National Park to spot sloths and monkeys, then cruise past massive ships on Gatún Lake.
  • Luxury Historic Living: Stay in the heart of Casco Viejo at a beautifully restored 17th-century Jesuit convent turned luxury design hotel.
  • Private Island Hideaway: Unwind in a beachfront casita on the 400-acre private resort of Isla Palenque, surrounded by seven pristine beaches and primary rainforest in the Gulf of Chiriquí.
Panamá Viejo, Vía Cincuentenario, Panamá

Panama City & Bocas del Toro

This dynamic Panamanian itinerary offers an ideal blend of historical exploration, iconic canal engineering, and eco-luxury coastal living. Transitioning from the energetic streets and rainforests surrounding Panama City to an exclusive overwater villa retreat in the Caribbean, it strikes a seamless balance between immersive guided discovery and all-inclusive tropical relaxation.

Duration: 7 Days / 6 Nights

Highlights:

  • Historic Panama City & Canal: Take in 360-degree views from Ancón Hill, sample fresh ceviche at the historic fish market, explore UNESCO-listed Casco Viejo, and enjoy VIP access to the Miraflores Locks on the Panama Canal.
  • Rainforest & Lake Expedition: Hike Soberanía National Park to spot howler monkeys and sloths, then navigate past massive container ships on a Gatún Lake boat tour.
  • Boutique Colonial Luxury: Stay in the heart of Casco Viejo at a restored 17th-century Jesuit convent transformed into a high-design luxury hotel.
  • Overwater Private Island Sanctuary: Relax on Frangipani Island at Nayara Bocas del Toro in an overwater pool villa with glass-floor marine viewing, private pools, and access to pristine snorkeling, mangroves, and Caribbean marine life.
Bocas Del Toro, Bocas Del Toro, Panama

Panama City Stopover

This rich Panamanian itinerary focuses on the deep history, engineering wonders, and vibrant Afro-Caribbean cultural traditions of the country. Based out of a landmark luxury hotel in Panama City’s historic district, it seamlessly combines iconic city sightseeing with a deep-dive cultural excursion to the Caribbean coast.

Duration: 4 Days / 3 Nights

Highlights:

  • Panama City & Canal Exploration: Take in 360-degree views from Ancón Hill, sample fresh local ceviche at the historic fish market, stroll through UNESCO-listed Casco Viejo, and enjoy VIP access to watch ships pass through the Miraflores Locks.
  • Portobelo Cultural Immersion: Travel across the isthmus to the historic Caribbean port town of Portobelo (a UNESCO site) to visit centuries-old Spanish forts, take a boat ride on Portobelo Bay, meet the local Congo queen, and witness a private Congo dance performance.
  • Community & Arts Connection: Visit La Escuelita del Ritmo in Portobelo to learn how music and dance are used for social inclusion and youth development in the local Afro-Caribbean community.
  • Boutique Historic Accommodation: Stay at a beautifully restored 17th-century Jesuit convent transformed into a luxury design hotel in the heart of Casco Viejo.
Casco Viejo, Panama City, Panama
Panama-Skyline

Panama City

Best Time to Visit: December–April

Panama City combines a modern skyline with the historic charm of Casco Viejo. Discover the city’s colonial past, explore the Panama Canal, enjoy its growing culinary scene, and use it as a gateway to the country’s extraordinary natural landscapes.

Boquete Panama

Boquete

Best Time to Visit: December–April

Set in the highlands of Chiriquí, Boquete offers cooler temperatures, dramatic mountain scenery, lush landscapes, and some of Panama’s finest coffee. Explore plantations, hike through cloud forest, and experience the region’s distinctive agricultural traditions.

Bocas Del toro Panama

Bocas del Toro

Best Time to Visit: February–April & September–October

The Bocas del Toro archipelago offers a laid-back Caribbean escape surrounded by turquoise waters, tropical forests, and beautiful beaches. Explore the islands by boat, snorkel and swim in the Caribbean, discover local communities, or simply slow down at a carefully selected island retreat.

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Joe helped us plan an absolutely incredible trip to Cuba. It was such an amazing learning experience and we felt like we were staying with our Cuban friends and family. Every detail was taken care of, we had such knowledgeable and friendly guides, the accommodations were superb, the food and entertainment experiences were wonderful. I can't say enough about this beautiful country, if you are considering it, go! I am so grateful we found Joe and Exeter to arrange one of the most memorable trips ever, and we are looking forward to working with them again! Update July 2026: Just returned from an amazing trip to Quito, Ecuador, the Galapagos and the Andes organized by Joe and his team. What an incredible experience - every detail was carefully organized so that we were able to maximize our time in this beautiful country and have a one of a kind adventure. We are always confident when working with Exeter that we will be connected to the best that any destination has to offer and this was no exception. Thank you Joe for facilitating a fabulous trip for us!
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Christine Kessler
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I had an amazing trip to the Galapagos and Ecuador with Exeter in July 2026. A small group, 18, excellent accommodations and food. Knowledgeable guides and friendly helpful staff. I will travel with Exeter again!
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Louise Leef
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This was our second time working with Kyle, at Exeter Latin America, and the trips are wonderful. Kyle is an excellent collaborator and was integral in creating a well thought out Peru itinerary that achieved our travel objectives. The hotels, guides, and travel arrangements were excellent. We look forward to planning our next Latin American trip with Kyle.
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Robert Dressler
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Joe Sandillo with Exeter South America assisted us with organizing our Brazil trip to Anavilhanas Lodge, including fly fishing arrangements and transportation coordination. Everything generally went smoothly, and it was helpful having someone coordinate the logistics for a more complicated international trip. We enjoyed the experience and appreciated the support with planning.
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cori criss
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Laly was amazing to work with-resourceful and responsive and put together a perfect itinerary that was executed seamlessly.
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Ashley Mehbod
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Exeter Latin America and Joe Sandillo were great in planning our travels. We were in Chile for three weeks and had six inland flights. They organized all our hotels and flights and everything went very smooth. They had given us great advice on where to stay, and guides they arranged for us also were fantastic.
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F Ten Brink
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Kyle helped us plan a fantastic family trip to Colombia. We all had a great time exploring and learning about the history of Colombia. Our accommodations were top notch, especially our home in the clouds - La Casa en La Nubes. An unforgettable treat! Our guides were super knowledgeable and enthusiastically shared their love for their country. We highly recommend!
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Pamela Frankel-Stein
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We had a fantastic trip and Exeter planned it perfectly. We're excited for our next trip back to Latin America and we will definitely be using them again.
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Linda Gordon
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Exeter Latin America and team did a wonderful job for our trip to Argentina. Everything was first rate. I would highly recommend Exeter, and am in fact taking my 3rd trip with them in March.
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Chuck Kalomeris
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With his knowledge of Mendoza and Buenos Aires and his relationships within these regions, Joe was able to provide us with an absolutely amazing experience - customized to our interests while also fitting in local history and culture. I would love to tour another Latin American country with Exeter and I highly recommend Joe's services to anyone interested in exploring this region.
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Aaron Miller

Frequently asked questions for your Panama trip

When is the best time to visit Panama?

December through April is generally the driest and most popular period to visit Panama. The country’s tropical climate means that rain is possible year-round, but its diverse regions can offer excellent experiences in different seasons.

Panama is ideal for a shorter journey, with even one week allowing travelers to combine Panama City with rainforest, mountains, or the coast. We generally recommend 5–10 days for a more relaxed experience.

We recommend planning at least four–six months in advance. For peak travel periods and smaller boutique properties or private island stays, earlier planning is recommended to secure the best availability.

Absolutely. The Canal is an important part of the country’s history, but Panama also offers tropical rainforests, cloud forests, islands, beaches, indigenous cultures, coffee plantations, and extraordinary biodiversity.

Panama City, Boquete, the Pacific coast, and Bocas del Toro are among the country’s highlights. The right combination depends on whether you prefer nature, adventure, culture, or relaxation.

Yes. Panama offers sophisticated city hotels, boutique mountain properties, private island retreats, luxury catamarans, and carefully curated nature experiences.

Panama City is well connected to the country’s major destinations by domestic flights, while private road transfers and boats are used to reach more remote areas and islands such as Bocas del Toro. Exeter Latin America arranges transportation as part of each private itinerary.

Panama is safe for our private journeys, with carefully selected hotels, guides, drivers, and local partners. Exeter Latin America works with partners we know and trust to provide reliable support throughout your journey.

Yes. Panama is particularly convenient for families because of its relatively compact geography and wide variety of experiences, from rainforest wildlife and beaches to the Panama Canal.